
David Gilmour's second solo on Comfortably Numb is regarded as the most emotionally devastating guitar solo in rock history. Every note bends with controlled anguish, and the sustained, singing tone Gilmour achieves on his Black Strat cuts through the orchestral arrangement like a voice crying out. Roger Waters has called it the best thing Gilmour ever played.
Reference:
TaskLoco™ — The Sticky Note GOAT